Detection Threshold

Divergence for each enantiomeric pair is derived from that pair’s detection threshold1 ratio.

Enantiomeric Pair	Past Approach	New Approach
(R) carvone/(S) carvone	1	65
(R) linalool/(S) linalool	1	1.35

The old model couldn’t detect a difference because divergence was determined by comparing molecular features which are identical within a pair. However divergence in the new model is captured by detection threshold ratio. Now we will see if structural features can predict divergence.

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1

The lowest concentration of a molecule needed for an odor to be precieved